Thanks Kenn, I checked and didn't see any permissions globally set for everyone, except the Create Ticket right is set for Everyone on each of our queues.<div><br></div><div>I made a few more changes though and am considering the problem fixed at this point. I found that the system was doing a lot of memory swapping, even though I increased the memory from 512MB with RT 3.8.8 (and MySQL) to 2GB with 4.0.5 (and Postgresql). I disabled all debugging and heavy logging, and adjusted the Apache configuration to increase the KeepAliveTimeout to 60 and reduce the MinSpareServers and MaxSpareServers. The apache processes were using between 60-100MB each (because of modperl I think), so if you have 15 apache processes running that's potentially 1.5GB. After making that change the system is "lightning fast" again. I still might add 1-2GB of memory just to be safe, I just didn't think that much should be necessary.</div>
<div><br></div><div>I also have rt-clean-sessions running every night, which should help some.</div><div><br></div><div>Thank you everyone that helped!</div>